A Toxicity Study of Thiamine Hydrochloride.
نویسندگان
چکیده
منابع مشابه
Thiamine hydrochloride (vitamin B1) as an efficient catalyst for the synthesis of 4-(3H)-Quinazolinone derivatives using grinding method.
Herein we explore facile synthesis of 4-(3H)-Qunazolinone derivatives, achieved by the cyclocondensation of anthranilic acid, aromatic amines and triethyl orthoformate in presence of thiamine hydrochloride (Vitamin B1) as a catalyst, using grinding method. This protocol offers several advantages such as reusability of catalyst, excellent yield, shorter reaction time and economic availability.Qu...
متن کاملThiamine hydrochloride (Vit-B1): An optimized green alternative for the synthesis of polyhydroquinoline derivatives
Thiamine hydrochloride (Vitamin-B1) has been utilized as an effective biodegradable catalyst for the one pot synthesis of polyhydroquinoline derivatives via four component reaction of dimedone, aldehyde, ethylacetoacetate and ammonium acetate in ethanol under mild conditions. The method presented here offers several advantages over reported procedures in terms of environmentally benign catalyti...
متن کاملThiamine hydrochloride (vitamin B1) as an efficient catalyst for the synthesis of 4-(3H)-Quinazolinone derivatives using grinding method.
Herein we explore facile synthesis of 4-(3H)-Qunazolinone derivatives, achieved by the cyclocondensation of anthranilic acid, aromatic amines and triethyl orthoformate in presence of thiamine hydrochloride (Vitamin B1) as a catalyst, using grinding method. This protocol offers several advantages such as reusability of catalyst, excellent yield, shorter reaction time and economic availability.Qu...
متن کاملThiamine hydrochloride (Vit-B1): An optimized green alternative for the synthesis of polyhydroquinoline derivatives
Thiamine hydrochloride (Vitamin-B1) has been utilized as an effective biodegradable catalyst for the one pot synthesis of polyhydroquinoline derivatives via four component reaction of dimedone, aldehyde, ethylacetoacetate and ammonium acetate in ethanol under mild conditions. The method presented here offers several advantages over reported procedures in terms of environmentally benign catalyti...
متن کاملPharmacokinetics of high-dose oral thiamine hydrochloride in healthy subjects
BACKGROUND High dose oral thiamine may have a role in treating diabetes, heart failure, and hypermetabolic states. The purpose of this study was to determine the pharmacokinetic profile of oral thiamine hydrochloride at 100 mg, 500 mg and 1500 mg doses in healthy subjects. METHODS This was a randomized, double-blind, single-dose, 4-way crossover study. Pharmacokinetic measures were calculated...
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عنوان ژورنال:
- Science
دوره 104 2711 شماره
صفحات -
تاریخ انتشار 1946